Helena J. Barr

This study shows microglia drive myelin loss in MS through autoantibodies and BTK signaling, with implications for therapeutic targeting.

This study identifies brain macrophages in the African turquoise killifish that engulf brain extracellular material, showing age-related decline in engulfment capacity.

This study generates and characterizes human brain border-associated macrophages (BAMs) using iPSC-derived models, showing a conserved hyper-endocytic phenotype across species.

This study identifies brain border-associated macrophages (BAMs) as rhythmic cells regulated by the circadian clock, showing that their endocytic activity and amyloid-beta uptake are disrupted with age and in a mouse model of Alzheimer's disease.

This study identifies the murine dura mater as a transient niche for early-postnatal B lymphopoiesis, highlighting the role of CXCL12-expressing fibroblasts in supporting B cell development.

This study shows that dopamine in the auditory cortex of zebra finches influences song preferences by altering incentive salience.

This study shows that motor learning after partial remyelination enhances remyelination by increasing oligodendrogenesis and myelin sheath generation.