Cell BiologybioRxivPreprint
UFMylation anchors splicing factors at the ER to reprogram nuclear splicing
Ni Zhan, Ranjith Kumar Papareddy, Bu Erte…·Yasin Dagdas
The paper identifies a retrograde signaling pathway where UFMylation of ER ribosomes anchors splicing factors at the ER, linking translational stress to nuclear RNA processing and altering membrane-associated gene expression.
DOI 10.64898/2026.03.30.715226