Aleksandra S. Anisimova

UFMylation anchors splicing factors at the ER to reprogram nuclear splicing

The paper identifies a retrograde signaling pathway where UFMylation of ER ribosomes anchors splicing factors at the ER, linking translational stress to nuclear RNA processing and altering membrane-associated gene expression.

Ancestral P-body proteins rewired for autophagic recyclingin the early land plant Marchantia polymorpha

This study identifies EDC4 and DCP1 as autophagy receptors for P-body turnover in Marchantia polymorpha, revealing lineage-specific adaptations and potential therapeutic applications.

Dual regulation of the unfolded protein response by IGF2BP3 during ER stress

This study shows IGF2BP3 regulates UPR effectors by stabilizing transcriptional regulators and destabilizing UPR target mRNAs during ER stress, modulating the UPR response.

The coordinated action of UFMylation and ribosome-associated quality control pathway clears arrested nascent chains at the endoplasmic reticulum

The paper shows UFMylation and RQC work together to clear stalled ER-bound ribosomes and arrested nascent chains.

Human tissues exhibit diverse composition of translation machinery

The paper analyzes transcriptomic and proteomic data to identify tissue-specific expression of translation machinery components and highlights sexual dimorphism in translation factors.

Multi-faceted deregulation of gene expression and protein synthesis with age

This study examines age-related changes in the transcriptome and translatome of mouse tissues, revealing U-shaped gene expression patterns and age-related declines in protein synthesis.

The comparative and genetic methods for East European Unionidae taxonomy

The paper uses comparative morphology and molecular genetics to study East European Unionidae mussels, finding that genetic methods better resolve species than morphology.