MicrobiologybioRxivPreprint
Stress-driven emergence of heritable non-genetic drug resistance
Jinglin Lucy Xie, Sifei Yin, Theodore S. Yang…·Daniel F. Jarosz
The paper identifies a non-genetic, heritable mechanism of drug resistance in Candida albicans triggered by subtherapeutic fluconazole exposure, which can be reversed and involves prion-like epigenetic processes.
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