Author

Sifei Yin

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1 Organism:yeast· 1 Organism:zebrafish· 1

Frequent Co-Authors

Daniel F. JarosziD· 3 shared Alejandro Sánchez AlvaradoiD· 1 shared Alice Y. TingiD· 1 shared Andrew S. McKayiD· 1 shared Anne BrunetiD· 1 shared Ben E. Machado· 1 shared Catherine Anne HoganiD· 1 shared Daniel HeinzeriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersGenetics

Daniel F. JaroszORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Towards CRISPR-based editing of the mitochondrial genome in yeast

Sifei Yin, Daniel F. Jarosz, Alice Y. Ting

This paper develops a method to edit mitochondrial DNA in yeast using CRISPR by identifying an RNA import motif that enables sgRNA delivery into mitochondria.

Proceedings of the National Academy of Sciences · Jan 16, 2026Peer-reviewedGenetics

Stress-driven emergence of heritable non-genetic drug resistance

Jinglin Lucy Xie, Sifei Yin, Theodore S. Yang, Kiran A. Chandrasekher, Luke Hanson, Sang Hu Kim, Lucas Esqueda, Catherine Anne Hogan, Niaz Banaei, June L. Round, Kyla S. Ost, Judith G. Berman, Daniel F. Jarosz

The paper identifies a non-genetic, heritable mechanism of drug resistance in Candida albicans triggered by subtherapeutic fluconazole exposure, which can be reversed and involves prion-like epigenetic processes.

bioRxiv · Dec 20, 2024 · PreprintMicrobiology

Identification of protein aggregates in the aging vertebrate brain with prion-like andphase separation properties

Itamar Harel, Yiwen R. Chen, Inbal Ziv, Param Priya Singh, Daniel Heinzer, Paloma Navarro Negredo, Uri Goshtchevsky, Wei Wang, Gwendoline Astre, Eitan Moses, Andrew S. McKay, Ben E. Machado, Katja Hebestreit, Sifei Yin, Alejandro Sánchez Alvarado, , Anne Brunet

The paper identifies prion-like and phase-separated protein aggregates in aging vertebrate brains using quantitative proteomics in killifish and validates their propagation and functional properties.

Cell Reports · May 28, 2024Peer-reviewedNeuroscience