Author

Shengnan Xia

Columbia University Irving Medical CenterORCID 0009-0001-3728-6669Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Juncheng LiiD· 2 shared Osama Al‐DalahmahiD· 2 shared Aayushi MahajaniD· 1 shared Adithya KannaniD· 1 shared Andrew S.J. YooiD· 1 shared Ashley S. HarmsiD· 1 shared David L. SulzeriD· 1 shared David CheniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Juncheng LiORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 27, 2026

The human-specific lncRNA HD-LINC drives lipid droplet-associated neurodegeneration in Huntington's disease

Ji‐Sun Kwon, Liyuan Wang, Naga R. Ganti…·Andrew S.J. Yoo

This study identifies HD-LINC, a human-specific lncRNA, as a driver of lipid droplet-associated neurodegeneration in Huntington's disease, showing its role in lipid metabolism and neuronal death.

DOI 10.64898/2026.10.23.761349

humanbulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedAug 4, 2025

The spatial landscape of glial pathology and T-cell response in Parkinson's disease substantia nigra

Maxwell Ma, Fahad Paryani, Kelly A. Jakubiak…·Osama Al‐Dalahmah

The paper analyzes T-cell responses and glial pathology in Parkinson's disease substantia nigra using single nucleus RNA sequencing and spatial transcriptomics, revealing CD8+ T-cell characteristics and altered cellular interactions.

49 citationstop 1%

humanscRNA-seq

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