Author

Sarah E. Clark

University of North Carolina at Chapel HillORCID 0009-0001-4478-8202Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Maik C. BischoffiD· 3 shared Mark A. PeiferiD· 3 shared Avery J. MathiasiD· 1 shared Corbin C. JenseniD· 1 shared Jenevieve E. NortoniD· 1 shared Joseph Dordor· 1 shared Kevin C. SlepiD· 1 shared Lawrencia Semireka Amo· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

Maik C. BischoffORCID

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3 papers

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedJul 29, 2026

A screen for adherens junction proteins regulating collective cell migration and testis morphogenesis reveals important roles for the Rab GAP RN-tre and the kinase Par-1

Sarah E. Clark, Siobhan Morris, Joseph Dordor…·Mark A. Peifer

The paper identifies junctional proteins critical for mesenchymal migration and testis morphogenesis in Drosophila using a combination of proximity proteomics and genome-wide shRNA screening.

DOI 10.1091/mbc.e26-05-0234

Drosophilagenetic perturbation / CRISPR

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Cell BiologyThe Journal of Cell BiologyPeer-reviewedSep 10, 2025

A key role for Canoes intrinsically disordered region in linking cell junctions to the cytoskeleton

Corbin C. Jensen, Noah J. Gurley, Avery J. Mathias…·Mark A. Peifer

The paper identifies conserved stickers in the Canoe IDR that bind F-actin, showing their combinatorial role in junctional localization, mechanosensing, and function during morphogenesis.

8 citations

Drosophilaproteomics

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Cell BiologyScience AdvancesPeer-reviewedJun 18, 2025

Plexin/Semaphorin Antagonism Orchestrates Collective Cell Migration, Gap Closure and Organ sculpting by Contact-Mesenchymalization

Maik C. Bischoff, Jenevieve E. Norton, Sarah E. Clark, Mark A. Peifer

The paper identifies a contact-dependent mechanism involving Plexin A and Semaphorin 1B that drives gap closure and organ sculpting during collective cell migration in Drosophila.

3 citations

Drosophilaexperimental assay

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