ImmunologyScience Translational MedicinePeer-reviewed
Impact of Human Genetic Variation Underlying Resistance to Antigen-Specific Immunotherapy
Romina Marone, Erblin Asllanaj, Giuseppina Capoferri…·Rosalba Lepore
This study identifies natural genetic variants in human therapeutic target antigens that can disrupt antibody binding, leading to resistance to antibody-based therapies.
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