Author

Yu Okuno

Scripps Research InstituteORCID 0009-0001-6887-3604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alia M. ObeidatiD· 1 shared Anne‐Marie MalfaitiD· 1 shared Bella Y. MehtaiD· 1 shared Dana E. OrangeiD· 1 shared Hannah SwahniD· 1 shared Hiroshi AsaharaiD· 1 shared Martin LotziD· 1 shared Merissa OlmeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alia M. ObeidatORCID

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1 paper

Recent·Most cited

Single-nucleus multiome profiling reveals osteocyte-centered remodeling of human subchondral bone across osteoarthritis severity

Yutaro Uchida, Hannah Swahn, Yu Okuno, Merissa Olmer, Alia M. Obeidat, Rachel E. Miller, Anne‐Marie Malfait, Miguel Otero, Bella Y. Mehta, Dana E. Orange, William D. Bugbee, Hiroshi Asahara, Martin Lotz

The paper uses single-nucleus multiome sequencing to analyze subchondral bone in OA, finding increased osteocyte SMAD2/3 activity and chondrocyte-derived FN1 signaling with disease severity.

bioRxiv · Oct 30, 2026 · PreprintMolecular Biology