Author

Bella Y. Mehta

Hospital for Special SurgeryORCID 0000-0003-2535-0974Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anne‐Marie MalfaitiD· 2 shared Dana E. OrangeiD· 2 shared Martin LotziD· 2 shared Miguel OteroiD· 2 shared Rachel E. MilleriD· 2 shared Accelerating Medicines Partnership: RA/SLE Network· 1 shared Alia M. ObeidatiD· 1 shared Caryn R. HaleiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Anne‐Marie MalfaitORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 30, 2026

Single-nucleus multiome profiling reveals osteocyte-centered remodeling of human subchondral bone across osteoarthritis severity

Yutaro Uchida, Hannah Swahn, Yu Okuno…·Martin Lotz

The paper uses single-nucleus multiome sequencing to analyze subchondral bone in OA, finding increased osteocyte SMAD2/3 activity and chondrocyte-derived FN1 signaling with disease severity.

DOI 10.64898/2026.10.29.762653

humanscRNA-seq

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GenomicsbioRxivPreprintApr 24, 2026

Synovial transcriptional clusters link cartilage degeneration to cell-type-specific gene expression in knee osteoarthritis

Michael R. Mazzucco, Bella Y. Mehta, Jenelys Ruiz Ortiz…·Dana E. Orange

The paper identifies four synovial transcriptional clusters in knee OA linked to cartilage degeneration severity through bulk and single-cell RNA-seq analyses.

1 citation

humanbulk RNA-seq

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