Author

Sydney J. Clifford

Purdue University West LafayetteORCID 0009-0001-7163-7581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Brittany L. Allen-PeterseniD· 2 shared Brittany N. HeiliD· 2 shared Claire M. PfefferiD· 2 shared Emily G. Smith· 2 shared Emma H. DoudiD· 2 shared Garima BaraliD· 2 shared Kasi HanseniD· 2 shared Lauren E. GartenhausiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Brittany L. Allen-PetersenORCID

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2 papers

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedApr 11, 2026

Suppression of PP2A-B56α Drives EMT in EGFR Mutant Non-Small Cell Lung Cancer

Brittany N. Heil, Garima Baral, Claire M. Pfeffer…·Brittany L. Allen-Petersen

This study shows that suppressing PP2A-B56α promotes EMT in EGFR mutant NSCLC by reducing epithelial markers and increasing mesenchymal markers, leading to migratory and invasive phenotypes.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 18, 2025

Activation of PP2A-B56α leads to aberrant EGFR signaling and proliferative phenotypes in PDAC

Claire M. Pfeffer, Sydney J. Clifford, Saadia A. Karim…·Brittany L. Allen-Petersen

This study shows that activating PP2A-B56 in PDAC increases EGFR signaling and promotes tumor growth, suggesting a new therapeutic target.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky