Coordinated tri-inhibition generates human CA1, CA3 and DG neurons and hippocampal astrocytes forming long-lived and electrophysiologically complex cultures
Kwaku Dad Abu-Bonsrah, Candice Desouza, Hui Wen Chan, Forough Habibollahi, Bradley Watmuff, Mirella Dottori, Brett J. Kagan
This paper develops a differentiation protocol to generate human hippocampal neurons and astrocytes in vitro, demonstrating long-term viability and electrophysiological complexity.
bioRxiv · Sep 30, 2026 · PreprintNeuroscience