Author
Scripps Research InstituteORCID 0000-0002-3077-802XUnclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Kaili Xue, F Rezayat, Tianbo Qi, Leyao Shen, Bohan Zhao, Xun Huang, Jonathan S. Marvin, Ye Li
The paper measures the energy cost of learning-based tasks in mice and finds that post-learning fuel consumption decreases, suggesting energy minimization during learning.
bioRxiv · Jul 2, 2026 · PreprintNeuroscience
Tianbo Qi, Colton Krull, Verina H. Leung, Vlad Mardare, Dong Yang, Neeraj Lal, Jingrui Ma, Shiqi Wang, Hanbing Shen, Alan Zhang, Bohan Zhao, Saba Heydari Seradj, Tatiana M. Korotkova, Ann Kennedy, Ye Li
The paper identifies a neural circuit regulating feeding bout fragmentation through activity in the dorsal subiculum to mammillary body pathway.
bioRxiv · Apr 3, 2026 · PreprintNeuroscience
Joseph P. Donnelly, Jan-Hannes Schäfer, Leonard Yoon, Lynée A. Massey, Carl T. Ash, Zi Gao, Karina Nugroho, Marcus Jäger, Zhengyuan Pang, Robert T. O'Neill, Mathew S. Maurer, Evan T. Powers, Gabriel C. Lander, Ye Li, Jeffery W. Kelly
This study uses proteomics and 3D imaging to show that ATTR cardiac amyloidosis involves microangiopathy, capillary occlusion, and vascular basement membrane congestion.
bioRxiv · Feb 11, 2026 · PreprintPathology
Zhengyuan Pang, Verina H. Leung, Cailynn C. Wang, Ahmadreza Attarpour, Anthony Rinaldi, Hanbing Shen, María Dolores Moya-Garzón, Logan H. Sigua, Claire Rammel, Alexandra Selke, Christopher Glynn, Melaina Yender, Senhan Xu, Javid J. Moslehi, Peng Wu, , Ye Li
This paper develops vCATCH to map covalent drug targets across the entire mouse body, revealing new tissue and cell type engagements for afatinib and ibrutinib.
Cell · Dec 22, 2025Peer-reviewedPharmacology & Toxicology
Yunxiao Zhang, Sejal A Kini, Sassan A Mishkanian, Renhao Luo, Saba Heydari Seradj, Verina H. Leung, Yu Wang, M. Rocio Servin‐Vences, William Thomas Keenan, Utku Sonmez, Oleg Yarishkin, Manuel Sánchez-Alavez, Yuejia Liu, Xin Jin, Darren J. Lipomi, , Ardem Patapoutian
Deleting Piezo1 and Piezo2 together in mice weakens uterine contractions and prolongs labor; uterine and sensory-neuron deletions act additively, and knockout uteri show reduced Gja1 (connexin43).
Science · Nov 13, 2025Peer-reviewedPhysiology✦ In-depth digest
Yu Wang, Yunxiao Zhang, Verina H. Leung, Saba Heydari Seradj, Utku M. Sönmez, M. Rocio Servin‐Vences, Shuke Xiao, Xiangyu Ren, Leon Wang, Sassan A Mishkanian, Sejal A Kini, Jonathan Z. Long, Darren J. Lipomi, Ye Li, Ardem Patapoutian
The paper identifies PIEZO2 as a key mechanosensitive ion channel in adipose sensory innervation and shows its role in regulating adipose tissue phenotypes.
Cell Metabolism · Mar 6, 2025Peer-reviewedNeuroscience
Dong Uk Yang, Yu Wang, Tianbo Qi, Xi Zhang, Leyao Shen, Jingrui Ma, Zhengyuan Pang, Neeraj K. Lal, Daniel B. McClatchy, Saba Heydari Seradj, Verina H. Leung, Kristina Wang, Yi Xie, Filip S. Polli, Anton Maximov, , Ye Li
The paper identifies phosphorylated pyruvate dehydrogenase (pPDH) as an in vivo marker for neuronal inhibition, correlating with reduced action potential firing and detectable across various inhibitory conditions.
Neuron · Jan 23, 2024Peer-reviewedNeuroscience
Neeraj K. Lal, Phuong Le, Samarth Aggarwal, Alan Zhang, Kristina Wang, Tianbo Qi, Zhengyuan Pang, Dong Yang, Victoria Nudell, Gene Wei-Ming Yeo, Alexander S. Banks, Ye Li
The paper identifies the xiphoid nucleus in the midline thalamus as a key region controlling cold-induced food seeking through neural activity and connectivity studies in mice.
Nature · Aug 16, 2023Peer-reviewedNeuroscience