Author

Simran Jit

Institute of Genomics and Integrative BiologyORCID 0009-0001-7816-6575Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Sherry BhallaiD· 3 shared Leepakshi Dhingra· 2 shared Deepika YadaviD· 1 shared Deepthi ShankaraniD· 1 shared Jitendra Kumar· 1 shared Kanika BishtiD· 1 shared Kirti JainiD· 1 shared Mahima Madan· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

Sherry BhallaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 10, 2026

Systematic Meta-Analysis of Published Transcriptomic Prognostic Signatures and Development of a Robust Multi-Cohort Prognostic Classifier for Triple-Negative Breast Cancer

Leepakshi Dhingra, Manulaya Singh, Simran Jit…·Sherry Bhalla

This study evaluates existing TNBC prognostic signatures and develops a robust 13-gene model with cross-cohort validation and therapeutic prioritization.

DOI 10.64898/2026.07.09.737472

humanbulk RNA-seq

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Genomicsnpj Systems Biology and ApplicationsPeer-reviewedOct 30, 2025

Alternative Promoters Drive Transcriptomic Reprogramming and Prognostic Stratification in TNBC

Simran Jit, Kirti Jain, Leepakshi Dhingra…·Sherry Bhalla

The paper identifies tumor-specific and subtype-specific alternative promoters in TNBC and develops a prognostic model based on these promoters, showing improved risk prediction.

1 citation

humanbulk RNA-seq

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ImmunologybioRxivPreprintJul 18, 2025

Macrophage Cholesterol Homeostasis Underpins the role of Sertraline as an Adjunctive Agent in Tuberculosis Therapy.

Kanika Bisht, Riya Sahu, Sneha Vasudevan…·Vivek Rao

This paper shows sertraline enhances macrophage bactericidal activity against Mtb by rewiring cholesterol metabolism and activating inflammasome pathways.

1 citation

humanbulk RNA-seq

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