Author

Jitendra Kumar

Institute of Genomics and Integrative Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Akhilesh Kumar Saini· 1 shared Deepthi ShankaraniD· 1 shared Kanika BishtiD· 1 shared Mahima Madan· 1 shared Nagasuma R ChandraiD· 1 shared Nikita Bhor· 1 shared Purnima TyagiiD· 1 shared Rajeev KhannaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Akhilesh Kumar Saini

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2 papers

Recent·Most cited

Macrophage Cholesterol Homeostasis Underpins the role of Sertraline as an Adjunctive Agent in Tuberculosis Therapy.

Kanika Bisht, Riya Sahu, Sneha Vasudevan, Simran Jit, Nikita Bhor, Jitendra Kumar, Mahima Madan, Deepthi Shankaran, Sherry Bhalla, Nagasuma R Chandra, Vivek Rao

This paper shows sertraline enhances macrophage bactericidal activity against Mtb by rewiring cholesterol metabolism and activating inflammasome pathways.

bioRxiv · Jul 18, 2025 · PreprintImmunology

DNA methylation and demethylation driven regulation of sepsis

Akhilesh Kumar Saini, Jitendra Kumar, Purnima Tyagi, Vipul Gautam, Rajeev Khanna, Vijay Kumar

This study investigates DNA methylation changes in sepsis, finding that transcription factor promoters are demethylated, potentially driving cytokine expression during inflammation.

bioRxiv · Sep 25, 2024 · PreprintMolecular Biology