Honey E. Mekonen

IG-28 identifies and quantifies high-confidence isoforms from large bulk and single-cell full-length cDNA datasets more effectively than existing tools.

The paper tracks antibiotic resistance gene (ARG) dynamics in mice during long-term antibiotic treatment, finding that commensal bacteria reduce ARG burden by outcompeting resistant taxa.

The paper presents Zebrahub-Multiome, a single-cell multiomic atlas of zebrafish embryogenesis, revealing gene regulatory network dynamics and cis-regulatory elements across developmental stages.

The paper introduces R2C2+UMI, a method combining concatemeric consensus sequencing with UMIs to achieve ultra-accurate sequencing of amplicons on Oxford Nanopore sequencers.

This study uses single-nucleus RNA sequencing to analyze a mouse glioblastoma model, identifying potential therapeutic targets and similarities with human GBM subtypes.

Zebrafish embryos sequenced individually across ten developmental stages, paired with light-sheet lineage reconstruction, form an atlas and browser for in silico fate mapping.