Masakazu Kotaka

The paper examines gut microbiome changes in chronic systolic heart failure patients, linking microbiome alterations to disease severity and clinical improvement.

This study shows that gut microbiome recovery after antibiotics is path-dependent, shaped by ecological and evolutionary dynamics including strain sweeps, genetic changes, and phage activity.

Eubiota enables autonomous discovery in the gut microbiome by integrating modular agents and reinforcement learning, identifying key pathways and designing therapeutic interventions.