Jessie L. Maier

TrIdent - An R package to automate transductomics analysis of virus-like particle mediated DNA mobilization

TrIdent automates transductomics analysis by identifying DNA mobilized by virus-like particles, showing high agreement with manual classifications and revealing enriched bacterial families in murine gut transductomes.

Perturbations shift the composition of bacterial DNA carried by virus-like particles in the murine gut microbiome

The paper analyzes the murine gut transductome before and after perturbations to identify bacterial families and mobile genetic elements involved in horizontal gene transfer.

High throughput chromatographic ultra-purification of virus-like particles for downstream viromics

This paper introduces an anion exchange chromatography method for purifying virus-like particles (VLPs) that outperforms CsCl in throughput and reproducibility while maintaining similar purity levels.

Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages

This study identifies phase variation of capsular polysaccharides and other resistance mechanisms as key strategies enabling stable coexistence between gut Bacteroidales and their lytic bacteriophages.

Dietary protein source alters gut microbiota composition and function

This study shows that different dietary protein sources alter gut microbiota composition and function in mice, affecting amino acid and mucus degradation processes.

Pseudo-pac site sequences used by phage P22 in generalized transduction of Salmonella

This study identifies pseudo-pac site sequences in Salmonella genomes that enable P22 phage to initiate generalized transduction, using bioinformatics analysis of sequencing data.