Colin Hill

This paper identifies herbicolin A, an antifungal lipopeptide from Pantoea agglomerans, as a promising natural biocontrol agent with low cytotoxicity and stability against food spoilage fungi.

The paper identifies gut phages with adhesin proteins that bind epithelial cells and traffic to the endoplasmic reticulum, revealing potential interactions with the human virome.

This study identifies a phage-resistant sub-population of Eggerthella lenta in mice, linked to reversible genomic inversions and altered capsule production.

Ratatoskr automates retrieval of bacterial taxonomic type strain sequences and metadata, resolving nomenclature inconsistencies across databases.

The paper uses nanopore sequencing to analyze capsid-packaged DNA in gut microbiomes, finding bacterial DNA encapsidation is widespread and associated with specific bacterial families.

This paper investigates phage-pathogen interactions in vivo using Citrobacter rodentium and a novel lytic phage, showing stable coexistence without reducing bacterial burden or inflammation.

This study investigates mechanisms of bacterial resistance and co-existence with temperate bacteriophages in the human gut using longitudinal sampling and experimental evolution.

The paper presents a structure-based classification framework for Caudoviricetes using whole-proteome structural clustering to resolve distant viral relationships.

This study identifies phase variation of capsular polysaccharides and other resistance mechanisms as key strategies enabling stable coexistence between gut Bacteroidales and their lytic bacteriophages.

The paper profiles and compares the phageome of oral and gut sites across individuals, finding distinct phage compositions and high diversity in oral sites, particularly on the tongue.

This study compares 16 virome assembly tools across four datasets, finding that SPAdes (meta) performs best, but all assemblers have limitations due to low coverage and repeats.

VIGA is a de novo viral genome annotator that accurately identifies coding sequences and reduces non-informative annotations in viral (meta)genomics data.