Author

Jiuyin Xu

Chinese Academy of SciencesORCID 0009-0001-9411-955XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Canrong WuiD· 2 shared H. Eric XuiD· 2 shared Heng ZhangiD· 2 shared Wen HuiD· 2 shared Xinheng HeiD· 2 shared Antao DaiiD· 1 shared Chao ZhangiD· 1 shared Dehua YangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

Canrong WuORCID

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2 papers

Recent·Most cited

BiochemistryThe EMBO JournalPeer-reviewedOct 29, 2025

Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors

Yanli Wu, Heng Zhang, Jiuyin Xu…·H. Eric Xu

The paper presents cryo-EM structures of EP2 and EP4 receptors with antagonists, revealing structural differences that explain selectivity and binding modes.

9 citations

humancryo-EM

𝕏 PostBluesky

BiochemistryCell DiscoveryPeer-reviewedApr 1, 2025

Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs

Canrong Wu, Chao Zhang, Sanshan Jin…·H. Eric Xu

This study presents cryo-EM structures of hURAT1 bound with anti-gout drugs and uric acid, revealing transport mechanisms and drug inhibition.

28 citationstop 1%

humancryo-EM

𝕏 PostBluesky