Pengfei Ji

This study shows that shear stress conditioning of porcine endocardial endothelial cells induces a pro-inflammatory response, mediated by CD31 and involving PI3K-AKT and TNF-a signaling pathways.

This study shows that shear stress in porcine endothelial cells releases cytokines that trigger fibrotic responses in cardiac fibroblasts, contributing to discrete subaortic stenosis.

This study identifies molecular differences in pulmonary vein stenosis (PVS) subtypes using bulk RNA sequencing, highlighting PIEZO1 overexpression and its role in aggressive PVS through extracellular matrix and calcium signaling changes.