Sundeep G. Keswani

This study shows that shear stress on macrophages increases their secretion of inflammatory factors, which in turn increases endothelial permeability and contributes to fibrosis in discrete subaortic stenosis.

This study shows that shear stress in porcine endothelial cells releases cytokines that trigger fibrotic responses in cardiac fibroblasts, contributing to discrete subaortic stenosis.