Alternative promoters used during myeloid differentiation and upon activation change the gene products available for innate immune programs.
Miguel Ángel Berrocal-Rubio, Josie Gleeson, Masaki Kato, Diane Delobel, Hitesh Kore, Anthony G Beckhouse, Dipti Vijayan, Kelly J Hitchens, Takeya Kasukawa, Chi Wai Yip, Chen Zhan, Michael B. Clark, Benjamin L. Parker, Hazuki Takahashi, Piero Carninci, , Christine Anne Wells
The paper identifies new gene products and transcript isoforms in macrophage differentiation and activation, revealing how alternative promoters influence innate immune functions.
bioRxiv · Feb 3, 2026 · PreprintGenomics