Pharmacology & ToxicologyAging CellPeer-reviewed
Atypical tetracyclines promote longevity and ferroptotic neuroprotection via translation attenuation
Khalyd J. Clay, Manuel Sánchez-Alavez, Ian Newman…·Michael Petrascheck
This paper identifies atypical tetracyclines that promote longevity and neuroprotection by inhibiting cytosolic translation, independent of classical mechanisms and antibiotic activity.