Author

Davide Silvestri

University of BolognaORCID 0009-0002-1852-5131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:virus· 1

Frequent Co-Authors

Christopher L. CioffiiD· 1 shared Gaetano Thomas MontelioneiD· 1 shared Luca MazzeiiD· 1 shared Rebecca Greene-CrameriD· 1 shared Sofia RanieriiD· 1 shared Stefano CiurliiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Christopher L. CioffiORCID

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1 paper

Recent·Most cited

BiochemistryScientific ReportsPeer-reviewedDec 31, 2024

An isothermal calorimetry assay for determining steady state kinetic and enzyme inhibition parameters for SARS-CoV-2 3CL-protease

Luca Mazzei, Sofia Ranieri, Davide Silvestri…·Stefano Ciurli

This paper develops an ITC assay to measure kinetic and inhibition parameters of SARS-CoV-2 3CL-protease, revealing two inhibition modes and deriving kinetic constants with high precision.

7 citations

virusexperimental assay

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