Author

Iria Laura Martinez

Umeå UniversityORCID 0009-0002-2219-5366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Eirini AntoniouiD· 1 shared Henrik LindehelliD· 1 shared Ilknur Safak Demirel· 1 shared Jakob J. E. StenmaniD· 1 shared Jiacheng ZhuiD· 1 shared Johan HolmbergiD· 1 shared Jonas MuhriD· 1 shared Juan Yuan· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Eirini AntoniouORCID

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1 paper

Recent·Most cited

HIF2α negatively regulates MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastoma.

Juan Yuan, Subhamita Maitra, Eirini Antoniou, Jiacheng Zhu, Wenyu Li, Ilknur Safak Demirel, Kostantinos Toskas, Iria Laura Martinez, Lacin Ozcimen, Henrik Lindehell, Jonas Muhr, Jakob J. E. Stenman, Per Kogner, Oscar C. Bedoya-Reina, Susanne Schlisio, Johan Holmberg

This paper shows that HIF2α reduces MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastoma, suggesting HIF2 has tumor suppressor rather than oncogenic function.

Proceedings of the National Academy of Sciences · Oct 21, 2025Peer-reviewedCancer Biology