Author

Jian Chen

Sun Yat-sen University Cancer CenterORCID 0009-0002-2472-6626Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jian Chen5 papers · Commonwealth Scientific and Industrial Research Organisation

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Chuting Zeng· 1 shared Cor LieftinkiD· 1 shared Feng Wang· 1 shared Gabriele Casagrande Raffi· 1 shared Jian ZhengiD· 1 shared Jing WangiD· 1 shared Jinzhe Mo· 1 shared Liesbeth HoekmaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Chuting Zeng

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedDec 18, 2024

An antibiotic that mediates immune destruction of senescent cancer cells

Gabriele Casagrande Raffi, Jian Chen, Xuezhao Feng…·Liqin Wang

This paper identifies SLC25A23 as a vulnerability in senescent cancer cells and shows that salinomycin induces immunogenic cell death, enhancing immune destruction of these cells when combined with a DR5 agonistic antibody.

15 citations

humanproteomics

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