Author

Shailesh Senthil Kumar

Columbia University Irving Medical CenterORCID 0009-0002-2653-5946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Chin Nien LeeiD· 2 shared Daniel Oh· 2 shared David E. Reynolds· 2 shared Emily HuynhiD· 2 shared Jianhua Lim· 2 shared Jina KoiD· 2 shared Junhyong KimiD· 2 shared Phoebe Vallapureddy· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Chin Nien LeeORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintNov 4, 2026

Live Droplet Single-Cell RNA Sequencing

David E. Reynolds, Sangmo Lee, Daniel Oh…·Jina Ko

The paper introduces Live D-seq, a method for longitudinal, non-destructive single-cell RNA sequencing, and demonstrates its ability to track cellular dynamics over time.

DOI 10.64898/2026.11.03.763484

humanscRNA-seq

𝕏 PostBluesky

BioengineeringbioRxivPreprintOct 30, 2026

Live Spatial Transcriptomics Enables Longitudinal Tissue Mapping

David E. Reynolds, Sangmo Lee, Chin Nien Lee…·Jina Ko

This paper introduces Live-ST, a method for longitudinal spatial transcriptomics, and demonstrates its use in tracking drug response in melanoma tissues.

DOI 10.64898/2026.10.28.761959

humanspatial transcriptomics

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NeuroscienceNature CommunicationsPeer-reviewedAug 4, 2025

The spatial landscape of glial pathology and T-cell response in Parkinson's disease substantia nigra

Maxwell Ma, Fahad Paryani, Kelly A. Jakubiak…·Osama Al‐Dalahmah

The paper analyzes T-cell responses and glial pathology in Parkinson's disease substantia nigra using single nucleus RNA sequencing and spatial transcriptomics, revealing CD8+ T-cell characteristics and altered cellular interactions.

49 citationstop 1%

humanscRNA-seq

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