Author

Virginia Apostolopoulou

Deutsches Elektronen-Synchrotron DESYORCID 0009-0002-2773-4111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Alisia FadiniiD· 1 shared Andreas PresteriD· 1 shared Caitlin E. HattoniD· 1 shared Eike C. SchulziD· 1 shared Friedjof TellkampiD· 1 shared Jasper J. van ThoriD· 1 shared Maria SpiliopoulouiD· 1 shared P. MehrabiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Alisia FadiniORCID

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2 papers

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedSep 15, 2026

Best practices for cryo-trapping time-resolvedcrystallography with the Spitrobot crystal plunger

Robert Bosman, Caitlin E. Hatton, Andreas Prester…·Eike C. Schulz

This paper describes a protocol for cryo-trapping time-resolved crystallography using automated crystal plungers to study enzyme reaction pathways at millisecond resolution.

DOI 10.1002/pro.70741

structural biologyexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintNov 6, 2024

Denoising Reveals Low-Occupancy Populations in Protein Crystals

Alisia Fadini, Virginia Apostolopoulou, Thomas J. Lane, Jasper J. van Thor

This paper improves difference map quality in protein crystallography by using negentropy and total variation denoising to better detect low-occupancy states.

DOI 10.1101/2024.11.06.622276

protein structuredeep learning

𝕏 PostBluesky