Christian Münch

This study evaluates proteomic screening strategies that enable high-throughput analysis without automation or expensive instrumentation upgrades.

This paper identifies immunomodulatory endothelial cells (IMEC) that present antigens on MHC class II and activate T cells in atherosclerosis.

This study identifies nuclear eNOS's role in modulating ADAR1 activity and type I interferon signaling, linking NO bioavailability to endothelial function and atherogenesis.

This study shows that the RNF4 ligand CCW16 induces ferroptosis in AML cells through a RNF4-independent mechanism by causing covalent protein modifications and upregulating ferroptosis markers.

This study identifies QKI as a regulator of splicing fidelity during cardiogenesis by interacting with U6 snRNA to enhance splicing at weak 5' splice sites.

This study identifies that phosphoribosyl ubiquitination of SNARE proteins STX17 and SNAP29 by Legionella SidE effectors regulates autophagy hijacking during infection.

The paper identifies N6AMT1's role in cytosolic translation of mitochondrial RNAse P subunits, showing its necessity for mitochondrial RNA processing and function.

The paper analyzes the phosphoproteome and interactome of a SCA2/ALS13 mouse model to identify altered signaling and protein interactions linked to neurodegeneration.

This study identifies a molecular pathway involving ARRB2 and RARRES1 that regulates the transition from liver fibrosis to cancer, with implications for diagnostics and therapeutics.

DynaTMT simplifies analysis of combined SILAC/TMT proteomics data by providing a browser-based tool and Python package for automated data extraction.

This study identifies growth factor receptor signaling as a key pathway for SARS-CoV-2 replication and shows that inhibiting it prevents viral replication in human cells.