Author

Charles R. Crain

Ragon Institute of MGH, MIT and HarvardORCID 0009-0002-3350-2501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aljawharah AlrubayyiiD· 2 shared Anna K. TraunbaueriD· 2 shared Gaurav D. GaihaiD· 2 shared Georg M. LaueriD· 2 shared Aarthi VijayakumariD· 1 shared Adam J. GehringiD· 1 shared Alex K. ShalekiD· 1 shared Alex S. GenshaftiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

Aljawharah AlrubayyiORCID

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2 papers

Recent·Most cited

NK-like and networked CD8+ T cell immunity mediates exceptional HIV control

Aljawharah Alrubayyi, Anna K. Traunbauer, Charles R. Crain, Shaown Bhattacharyya, David R. Collins, Hsinyen Huang, Clarety Kaseke, Umar Arshad, Xiaodong Lian, Aarthi Vijayakumar, Matthew A. Getz, Mathias D. Lichterfeld, Xu G. Yu, Bruce D. Walker, Georg M. Lauer, Gaurav D. Gaiha

The paper identifies an NK-like KIR CD8 T cell subset as a key feature of exceptional HIV control, complementing networked epitope targeting for immunotherapeutic strategies.

bioRxiv · Jul 7, 2026 · PreprintImmunology

CD8 T cells with classical and NK-like cytotoxic gene expression programs mediate control of HBV replication and functional cure

Elias Isaac Lattouf, Martin Feuerherd, Lea M. Bartsch, Hannah K. Drescher, Suzan Dijkstra, Martin Arreola Villanueva, Ruben C. Hoogeveen, David Lieb, Koen Van den Berge, Ewoud De Troyer, Sonu Subudhi, Alex S. Genshaft, Nádia Conceição‐Neto, Anna K. Traunbauer, Aljawharah Alrubayyi, , Georg M. Lauer

The paper identifies two distinct CD8 T cell gene expression programs in HBV infection that correlate with viral control and functional cure.

bioRxiv · Jun 29, 2026 · PreprintImmunology