Author

Hsinyen Huang

Ragon Institute of MGH, MIT and HarvardORCID 0009-0005-2903-8322Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Aljawharah AlrubayyiiD· 2 shared Anna K. TraunbaueriD· 2 shared Gaurav D. GaihaiD· 2 shared Matthew A. GetziD· 2 shared Shaown BhattacharyyaiD· 2 shared Aarthi VijayakumariD· 1 shared Alton Gayton· 1 shared Alyne Nascimento· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Aljawharah AlrubayyiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 25, 2026

Effector-primed TCF1+ CD8+ T cells elicited by a networked epitope vaccine stratify protection against SHIV acquisition

Matthew A. Getz, Aljawharah Alrubayyi, Mariane Melo…·Gaurav D. Gaiha

This study identifies an effector-primed TCF1+ CD8+ T cell state linked to delayed SHIV acquisition and reduced viral load in vaccinated non-human primates.

DOI 10.64898/2026.10.20.760588

non-human primatescRNA-seq

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ImmunologybioRxivPreprintJul 7, 2026

NK-like and networked CD8+ T cell immunity mediates exceptional HIV control

Aljawharah Alrubayyi, Anna K. Traunbauer, Charles R. Crain…·Gaurav D. Gaiha

The paper identifies an NK-like KIR CD8 T cell subset as a key feature of exceptional HIV control, complementing networked epitope targeting for immunotherapeutic strategies.

DOI 10.64898/2026.07.02.735504

humanbulk RNA-seq

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Synthetic BiologyNature Biomedical EngineeringPeer-reviewedAug 15, 2025

Engineered bacteria launch and control an oncolytic virus

Zakary S. Singer, Jonathan Pabón, Hsinyen Huang…·Tal Danino

This paper describes engineered bacteria that deliver a viral genome to initiate oncolytic infection in tumors, demonstrating bacterial control over viral replication.

48 citationstop 1%

bacteria (other)mouse

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