Matthew A. Getz

Effector-primed TCF1+ CD8+ T cells elicited by a networked epitope vaccine stratify protection against SHIV acquisition

This study identifies an effector-primed TCF1+ CD8+ T cell state linked to delayed SHIV acquisition and reduced viral load in vaccinated non-human primates.

NK-like and networked CD8+ T cell immunity mediates exceptional HIV control

The paper identifies an NK-like KIR CD8 T cell subset as a key feature of exceptional HIV control, complementing networked epitope targeting for immunotherapeutic strategies.

Non-clinical safety of GRAd vector-based COVID-19 and HIV vaccines supports a platform regulatory approach

This study evaluates the non-clinical safety of two GRAd vector-based vaccines for COVID-19 and HIV, showing consistent safety profiles and supporting a regulatory platform approach.

Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection

Xrn1p Acts at Multiple Steps in the Budding-Yeast RNAi Pathway to Enhance the Efficiency of Silencing

The paper identifies Xrn1p as a cofactor in the budding-yeast RNAi pathway, showing it enhances silencing through multiple functions.