Joseph O. Armstrong

The paper investigates the mcm4Chaos3 mutation in yeast, showing it causes genome instability by impairing specific centromere-proximal origins.

The paper investigates rDNA instability in aging yeast, identifying new forms of instability beyond ERCs that contribute to lifespan variability.

This paper uses experimental evolution to improve mother-daughter separation defects in brewing yeast by generating evolved strains with reduced clustering.

The paper identifies URA6 mutations that confer 5-FOA resistance in yeast, showing cross-resistance to other fluorinated compounds and revealing a reduction in uridylate kinase activity.

The paper systematically profiles protein dynamics in ale yeast during fermentation and repitching, identifying changes in ergosterol and isobutyraldehyde metabolism.