Author

Mahesh Subramanian

Bhabha Atomic Research CentreORCID 0009-0002-3749-2224Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ananda Guha MajumdariD· 2 shared Birija Sankar PatroiD· 2 shared Nitish ChauhaniD· 2 shared Papiya DeyiD· 1 shared Pooja GuptaiD· 1 shared Sujit K. BhutiaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

Ananda Guha MajumdarORCID

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2 papers

Recent·Most cited

Cancer BiologyThe EMBO JournalPeer-reviewedMay 13, 2026

CHK1-mediated regulation of TOP1 catalytic activity suppresses replication and transcription-associated genomic instability

Ananda Guha Majumdar, Nitish Chauhan, Pooja Gupta…·Birija Sankar Patro

This study identifies CHK1's role in phosphorylating TOP1 to regulate its catalytic cycle and prevent genomic instability in cancer.

1 citation

humanDNA methylation

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Cancer BiologybioRxivPreprintSep 7, 2025

Targeting a novel chloroquine derivative to lysosomes induces massive and irreversible damage to lysosomes and suppresses autophagosomes and lysosomes assembly in cancer

Nitish Chauhan, Ananda Guha Majumdar, Sujit K. Bhutia…·Birija Sankar Patro

This paper develops a novel chloroquine derivative, Lysostilbene-4, which irreversibly damages lysosomes and suppresses their recovery in pancreatic cancer cells.

DOI 10.1101/2025.09.07.674530

humanproteomics

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