Author

Birija Sankar Patro

Bhabha Atomic Research CentreORCID 0000-0001-9161-5913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ananda Guha MajumdariD· 3 shared Mahesh SubramanianiD· 2 shared Nitish ChauhaniD· 2 shared Pooja GuptaiD· 2 shared Sujit K. BhutiaiD· 2 shared Avik ChakrabortyiD· 1 shared Ganesh Pai BellareiD· 1 shared Megha Tawate· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

Ananda Guha MajumdarORCID

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3 papers

Recent·Most cited

Cancer BiologyThe EMBO JournalPeer-reviewedMay 13, 2026

CHK1-mediated regulation of TOP1 catalytic activity suppresses replication and transcription-associated genomic instability

Ananda Guha Majumdar, Nitish Chauhan, Pooja Gupta…·Birija Sankar Patro

This study identifies CHK1's role in phosphorylating TOP1 to regulate its catalytic cycle and prevent genomic instability in cancer.

1 citation

humanDNA methylation

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Cell BiologybioRxivPreprintDec 14, 2025

WRN helicase regulates mitophagy by resolving an intricate nexus of G-quadruplexes-R loops-ATG7 pre-mRNA maturation in cancer

Pooja Gupta, Mrityunjay Tyagi, Ananda Guha Majumdar…·Birija Sankar Patro

This paper identifies WRN's role in regulating mitophagy and autophagy in cancer by resolving G-quadruplexes and R-loops to enable proper ATG7 mRNA processing.

DOI 10.64898/2025.12.11.692796

humanDNA methylation

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Cancer BiologybioRxivPreprintSep 7, 2025

Targeting a novel chloroquine derivative to lysosomes induces massive and irreversible damage to lysosomes and suppresses autophagosomes and lysosomes assembly in cancer

Nitish Chauhan, Ananda Guha Majumdar, Sujit K. Bhutia…·Birija Sankar Patro

This paper develops a novel chloroquine derivative, Lysostilbene-4, which irreversibly damages lysosomes and suppresses their recovery in pancreatic cancer cells.

DOI 10.1101/2025.09.07.674530

humanproteomics

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