Nitish Chauhan

This study identifies CHK1's role in phosphorylating TOP1 to regulate its catalytic cycle and prevent genomic instability in cancer.

This paper develops a novel chloroquine derivative, Lysostilbene-4, which irreversibly damages lysosomes and suppresses their recovery in pancreatic cancer cells.

This paper introduces a novel photosensitizer, NbB, for targeted photodynamic therapy and dual imaging of ER and LD in PDAC, showing efficient triplet state generation and apoptosis.