Molecular BiologybioRxivPreprint
The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses
Shixin Cui, Nicole L. Batenburg, Yan Coulombe…·Xu‐Dong Zhu
This study identifies ASCC3 as a helicase that unwinds DNA at stalled replication forks, promoting fork reversal and preventing genomic instability during replication stress.
DOI 10.1101/2025.07.24.666583