Author

John R. Walker

McMaster UniversityORCID 0000-0002-5255-895XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrew S. HaganiD· 1 shared Anja‐Katrin BielinskyiD· 1 shared Aruna ArumugamiD· 1 shared Bao Nguyen· 1 shared Bin FangiD· 1 shared Brandon L. Taylor· 1 shared Casey J. N. MathisoniD· 1 shared Dean P. PhillipsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Andrew S. HaganORCID

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2 papers

Recent·Most cited

The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses

Shixin Cui, Nicole L. Batenburg, Yan Coulombe, Aruna Arumugam, John R. Walker, Sadaf Valeh Sheida, Anja‐Katrin Bielinsky, M.C. Wahl, Jean‐Yves Masson, Xu‐Dong Zhu

This study identifies ASCC3 as a helicase that unwinds DNA at stalled replication forks, promoting fork reversal and preventing genomic instability during replication stress.

bioRxiv · Jul 24, 2025 · PreprintMolecular Biology

AHR activation accelerates the resolution of TGF-β1 induced fibroblast activation and promotes alveolar type 1 cell regeneration in alveolar organoids

Andrew S. Hagan, Scott Williams, Casey J. N. Mathison, Shanshan Yan, Bao Nguyen, Glenn C. Federe, Guray Kuzu, Joseph C. Siefert, Janice Hampton, Victor Chichkov, S. Whitney Barnes, Frederick J. King, Brandon L. Taylor, John R. Walker, Rui Zhao, , Rebekah S. Decker

The paper identifies DB-11-BE87 as a compound that promotes AT1 cell regeneration by reducing TGF-β1-induced fibroblast activation through AHR activation in alveolar organoids.

Communications Biology · Jul 9, 2025Peer-reviewedCell Biology