Author

Tommy G. Primo

University of WashingtonORCID 0009-0002-4489-4168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Aria WallsiD· 1 shared Cholpisit KiattiseweeiD· 1 shared David Sparkman-Yager· 1 shared Héctor García MartíniD· 1 shared Ian FaulkneriD· 1 shared James M. CarothersiD· 1 shared Jason T. FontanaiD· 1 shared Jesse G. ZalataniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Aria WallsORCID

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1 paper

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedJul 27, 2024

Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling

Jason T. Fontana, David Sparkman-Yager, Ian Faulkner…·James M. Carothers

The paper designs guide RNA structures for CRISPRa to optimize multi-gene expression in bacterial metabolic pathways, achieving higher product titers and identifying pathway bottlenecks.

30 citationstop 4%

E. coliCRISPR screen

𝕏 PostBluesky