Author

Christina Paschou

Pasteur Hellenic InstituteORCID 0009-0002-4944-7869Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Chiara ZurzoloiD· 1 shared Era TaoufikiD· 1 shared Evangelia EmmanouilidouiD· 1 shared Florentia PapastefanakiiD· 1 shared Francesca PaleseiD· 1 shared Konstantina Charmpi· 1 shared Konstantina DimoulaiD· 1 shared Martina K. SamiotakiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Chiara ZurzoloORCID

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1 paper

Recent·Most cited

Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson's disease model with Lewy-like pathology

Christina Paschou, Olympia Apokotou, Αναστάσιος Κόλλιας, Konstantina Charmpi, Sofia Dede, Martina K. Samiotaki, Francesca Palese, Konstantina Dimoula, Evangelia Emmanouilidou, Era Taoufik, Chiara Zurzolo, Rebecca Matsas, Florentia Papastefanaki

This study shows that p.A53T-α-Synuclein astrocytes from Parkinson's patients impair proteostasis, leading to neurodegeneration and Lewy-like pathology in co-cultured neurons.

bioRxiv · Nov 6, 2024 · PreprintNeuroscience