Author

Florentia Papastefanaki

Pasteur Hellenic InstituteORCID 0000-0003-1237-642XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Rebecca MatsasiD· 2 shared Ahmad SaltiiD· 1 shared Chiara ZurzoloiD· 1 shared Christina PaschouiD· 1 shared Cláudia SaraivaiD· 1 shared Elisa GabassiiD· 1 shared Era TaoufikiD· 1 shared Evangelia EmmanouilidouiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Rebecca MatsasORCID

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2 papers

Recent·Most cited

Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson's disease model with Lewy-like pathology

Christina Paschou, Olympia Apokotou, Αναστάσιος Κόλλιας, Konstantina Charmpi, Sofia Dede, Martina K. Samiotaki, Francesca Palese, Konstantina Dimoula, Evangelia Emmanouilidou, Era Taoufik, Chiara Zurzolo, Rebecca Matsas, Florentia Papastefanaki

This study shows that p.A53T-α-Synuclein astrocytes from Parkinson's patients impair proteostasis, leading to neurodegeneration and Lewy-like pathology in co-cultured neurons.

bioRxiv · Nov 6, 2024 · PreprintNeuroscience

Age-induced midbrain-striatum assembloids model early phenotypes of Parkinsons disease

Kyriaki Barmpa, Cláudia Saraiva, Gemma Gomez‐Giro, Elisa Gabassi, Sarah Spitz, Konstanze Brandauer, Juan Eduardo Rodriguez-Gatica, Paul M. A. Antony, Graham Robertson, Florentia Papastefanaki, Ulrich Kubitscheck, Ahmad Salti, Peter Ertl, Rebecca Matsas, Frank Edenhofer, Jens Christian Schwamborn

This paper introduces midbrain-striatum assembloids with inducible aging to model early Parkinson's disease phenotypes and nigrostriatal connectivity.

bioRxiv · Oct 28, 2023 · PreprintNeuroscience