Author
Centre National de la Recherche ScientifiqueORCID 0000-0002-8426-8228Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Francesca Palese, Carmela Giachino, Sylvie Syan…·Chiara Zurzolo
This study identifies NAPEs as regulators of LRRK2 and lysosomal function in Parkinson's disease, showing that boosting NAPEs reduces LRRK2 activity and clears alpha-synuclein aggregates.
Ranabir Chakraborty, Francesca Palese, Philippa Samella…·Chiara Zurzolo
The paper shows that neuronal autophagy failure leads to α-synuclein aggregate transfer to microglia, which then degrade them more efficiently.
Christina Paschou, Olympia Apokotou, Αναστάσιος Κόλλιας…·Florentia Papastefanaki
This study shows that p.A53T-α-Synuclein astrocytes from Parkinson's patients impair proteostasis, leading to neurodegeneration and Lewy-like pathology in co-cultured neurons.