Kelly E. Dooling

Adrenergic signaling coordinates distant and local responses to amputation in axolotl

This paper shows that adrenergic signaling coordinates systemic and local stem cell activation after amputation in axolotls, enhancing regeneration.

An evolutionarily conserved role for VEGF signaling in the expansion of non-vascular tissue during regeneration.

This study shows VEGF signaling is essential for salamander limb regeneration and blastema expansion, independent of angiogenesis, and functions upstream of EMT transcription factors.

Amputation Triggers Long-Range Epidermal Permeability Changes in Evolutionarily Distant Regenerative Organisms

This study examines long-range epidermal permeability changes after amputation in axolotls and planarians, finding increased permeability and MAPK signaling downregulation in axolotls and functional evidence of MAPK inhibition increasing permeability in planarians.