Aaron M. Savage

This paper shows that adrenergic signaling coordinates systemic and local stem cell activation after amputation in axolotls, enhancing regeneration.

This study shows that pancreatic injury in axolotl leads to β-cell regeneration without blastema formation, through organ-wide proliferation that recovers β-cell mass.

This study shows VEGF signaling is essential for salamander limb regeneration and blastema expansion, independent of angiogenesis, and functions upstream of EMT transcription factors.

This study examines long-range epidermal permeability changes after amputation in axolotls and planarians, finding increased permeability and MAPK signaling downregulation in axolotls and functional evidence of MAPK inhibition increasing permeability in planarians.

The paper identifies asymmetric Hapln1a expression in zebrafish heart development, showing it drives ECM expansion and promotes asymmetric heart morphogenesis through interaction with laterality cues.

The paper describes the discovery of transient NO-containing spherical structures in zebrafish cerebral endothelial cells during development, showing their dependence on Notch signaling.

The paper investigates the roles of foxc1a and foxc1b in regulating angiogenesis from arteries and veins in zebrafish by modulating VEGF and Dll4/Notch signaling.