Author

Natasha Sharma

University College LondonORCID 0009-0002-5583-9834Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:multiome· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Andrea VenturaiD· 1 shared Andrew RowaniD· 1 shared Benjamin WerneriD· 1 shared Charles SwantoniD· 1 shared Chris BaileyiD· 1 shared Clare E. WeedeniD· 1 shared Davide PradellaiD· 1 shared Delphine BocheiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrea VenturaORCID

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1 paper

Recent·Most cited

Extrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastoma

Imran Noorani, Magnus J. Haughey, Jens Luebeck, Andrew Rowan, Eva Camilla Gronroos, Francesco Terenzi, Ivy Tsz-Lo Wong, Davide Pradella, Marta Lisi, Jeanette Clarissa Kittel, Natasha Sharma, Chris Bailey, Clare E. Weeden, Donald M. Bell, Eric Joo, , Benjamin Werner

This study investigates the spatial-temporal evolution of extrachromosomal DNA (ecDNA) in glioblastoma, showing that EGFR ecDNA drives tumor evolution and identifies a potential therapeutic window for early intervention.

Cancer Discovery · Sep 8, 2025Peer-reviewedCancer Biology