Author

Donald M. Bell

The Francis Crick InstituteORCID 0000-0002-3788-1580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Andrea VenturaiD· 1 shared Andrew RowaniD· 1 shared Benjamin WerneriD· 1 shared Charles SwantoniD· 1 shared Chris BaileyiD· 1 shared Clare E. WeedeniD· 1 shared Claudia GerriiD· 1 shared David J. BarryiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Andrea VenturaORCID

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3 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedSep 8, 2025

Extrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastoma

Imran Noorani, Magnus J. Haughey, Jens Luebeck…·Benjamin Werner

This study investigates the spatial-temporal evolution of extrachromosomal DNA (ecDNA) in glioblastoma, showing that EGFR ecDNA drives tumor evolution and identifies a potential therapeutic window for early intervention.

40 citationstop 1%

humanwhole-genome sequencing

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BioinformaticsJournal of Cell SciencePeer-reviewedMay 3, 2022

GIANI: open-source software for automated analysis of 3D microscopy images

David J. Barry, Claudia Gerri, Donald M. Bell…·Kathy K. Niakan

GIANI is an open-source software for automated analysis of 3D microscopy images, enabling segmentation, morphology quantification, and protein expression analysis in various imaging contexts.

14 citations

mousefungi (other)

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Developmental BiologyPLoS BiologyPeer-reviewedMay 17, 2021

Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak.

Kenzo Ivanovitch, Pablo Soro-Barrio, Probir Chakravarty…·James Briscoe

The paper identifies spatial and molecular differences in cardiac progenitor origins in mouse embryos, showing distinct regions of the primitive streak contribute to different heart structures.

111 citationstop 1%

mousescRNA-seq

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