Cell BiologyeLifePeer-reviewed
Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells
Qi Zhang, Yunfeng Wang, Xueli Fu…·Shaowei Zhao
The paper identifies Uev1A and its human homologs as protectors against oncogenic Ras-induced cellular stress in both polyploid and diploid cells, showing their role in suppressing tumor growth and improving patient survival.
DOI 10.7554/elife.107104