Cancer BiologybioRxivPreprint
Improve the Efficacy of B7-H3-Targeting Antibody-Drug Conjugate DS-7300a in TP53-deficient Tumors by Inducing Ferroptosis
Javier Leo, Feiyu Chen, Wei Shi…·Di Zhao
This study shows that TP53-deficient tumors resist DS-7300a therapy, but inducing ferroptosis can enhance its efficacy in these cancers.
DOI 10.64898/2026.05.05.722958