Author

Hugo Amedei

Universitätsmedizin GöttingenORCID 0009-0002-6441-2648Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christof LenziD· 3 shared Brian FooiD· 2 shared Henning UrlaubiD· 2 shared Stephan E. LehnartiD· 2 shared Alfredo Cabrera‐OreficeiD· 1 shared Angela BoshnakovskaiD· 1 shared Esteban Palacios-Contreras· 1 shared Felix LangeiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

Christof LenzORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 17, 2026

AMPK reinforces mitochondrial metabolism and suppresses pathological remodeling in Complex V-deficient cardiomyocytes

Esteban Palacios-Contreras, Karen an der Brugge, Jakob Fell…·Mario Pávez

This study shows that AMPK activation rescues mitochondrial function and structural remodeling in TMEM70-deficient cardiomyocytes, highlighting a metabolic rescue mechanism in mitochondrial cardiomyopathy.

DOI 10.64898/2026.09.14.751384

humanproteomics

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Cell BiologyPLoS ONEPeer-reviewedOct 24, 2024

Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Delta/+ mice hearts

Brian Foo, Hugo Amedei, Surmeet Kaur…·Stephan E. Lehnart

8 citations

mouseproteomics

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Systems BiologyFrontiers in Analytical SciencePeer-reviewedAug 1, 2024

mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes

Hugo Amedei, Niels Benjamin Paul, Brian Foo…·Christof Lenz

The paper introduces mCP, a streamlined workflow for detecting protein complexes with reduced fractionation, and demonstrates its application in analyzing cardiac tissue.

1 citation

mouseproteomics

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